April 17, 2026
Temporary Restraining Order Granted: THCA Available Again & Other Updates
Through a process aided with heat and light called biosynthesis, CBGA can convert directly to its non-acidic form, CBG (cannabigerol), as well as to:
- THCA
- CBDA
- CBCA
Nevertheless, the scientific research on this compound is promising. Here are just a handful of the current findings on CBGA in peer-reviewed studies:
- Inhibition of aldose reductase, an enzyme involved in many diabetic complications
- Cytotoxicity on colon cancer cells
- Activating peroxisome proliferator activated receptors (PPARs) which help manage metabolism
Here is what studies have found so far about CBDA:
- May act as a selective inhibitor for cyclooxygenase (COX)-2, a compound in the human body that's a common target for anti-inflammatory drugs
- Having 100x the affinity for binding to 5-HT1A receptors compared to CBD, researchers have implicated 5-HT1A receptors in the cause and treatment of disorders such as depression and anxiety
- Results from a study about a CBDA derivative and obesity treatment support a clinical trial in humans