January 30, 2023
Two Rare Hemp Extracts You Need To Know About: CBGA & CBDA
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In June of 2022, CBGA and CBDA made waves when findings related to the compounds' potential prevention of coronavirus were published by researchers from Oregon State University. Several months later, the Hebrew University of Jerusalem published research on the efficacy of CBDA derivatives for treating obesity.
With all this groundbreaking research unfolding, perhaps you're wondering, what are CBGA and CBDA, and are these cannabinoids worth considering?
Below, we cover everything you need to know about these rare hemp compounds, including findings related to their potential applications for health.
What is CBGA?
CBGA stands for cannabigerolic acid. Found almost exclusively in young plants, many consider it to be the “mother of all cannabinoids” because it is the precursor to most cannabis compounds.
Through a process aided with heat and light called biosynthesis, CBGA can convert to:
- THCA
- CBDA
- CBCA
Israeli scientists Yehiel Gaoni and Raphael Mechoulam first identified CBG in 1964. A few decades later, in 1996, researchers at Kyushu University found that CBDA predominantly biosynthesizes from CBGA.
Scientific Findings on CBGA
It is important to note there is little to no clinical research on the effects of CBGA in living humans. There is, however, in vitro and silico research available on CBGA. The Food and Drug Administration has not evaluated CBGA products, and they are not intended to diagnose, treat, cure, or prevent any disease.
Nevertheless, the scientific research on this compound is promising. Here are just a handful of the current findings on CBGA in peer-reviewed studies:
- Inhibition of aldose reductase, an enzyme involved in many diabetic complications
- Cytotoxicity on colon cancer cells
- Activating peroxisome proliferate activated receptors (PPARs) which help manage metabolism
What is CBDA?
CBDA stands for cannabidolic acid. It is one of the byproducts of CBGA and the direct precursor to CBD. CBDA converts to CBD via decarboxylation, a chemical reaction that removes a carboxyl group from a molecule.
When you purchase CBD flower, a lot of what you get (at first) is actually CBDA. By combusting the flower or heating it, you can decarboxylate it, thus receiving the effects of CBD. However, finding bioavailable CBDA on its own in the hemp market is difficult.
Scientific Findings on CBDA
Much like CBGA, it's important to note that products that contain CBDA products are not meant to diagnose, cure, or treat any medical condition. The findings below are for general information and should not be taken as medical advice.
Here is what studies have found so far about CBDA:
- May act as a selective inhibitor for cyclooxygenase (COX)-2, a compound in the human body that's a common target for anti-inflammatory drugs
- Having 100x the affinity for binding to 5-HT1A receptors compared to CBD, researchers have implicated 5-HT1A receptors in the cause and treatment of disorders such as depression and anxiety
- Results from a study about a CBDA derivative and obesity treatment support a clinical trial in humans
Shopping for CBDA + CBGA Products
As mentioned earlier, CBDA and CBGA are rare in the commercial market. However, they are not impossible to find. Several reputable hemp brands carry tinctures that contain these two cannabinoids.
So what should you look for when shopping for a CBDA + CBGA tincture?
Lab Results
You should never purchase any hemp product that does not come with a COA.
What is a COA? COA stands for "certificate of analysis." They're third-party lab reports indicating the contents of what you're purchasing and that it's free of contaminants.
Reviews
Don't take their word on it. See what customers are saying about their products. Whether you are purchasing a CBDA + CBGA tincture or any other hemp product, it's always a good idea to check customer reviews to see if the product they're selling is quality.
In-house Customer Support
Sure, just about any company has a customer support team. But too often, it's outsourced personnel who may not have experience with the products. When a hemp company has an in-house customer support team, your questions, concerns, and needs are addressed by those with hands-on experience with your purchased products.
CBDA + CBGA Tincture
If you want to try these rare cannabinoids, you're in luck because we sell them online. Our CBDA + CBGA tincture contains 600mg CBDA, 600mg CBGA, 600mg CBD, and 600mg CBG. We also use MCT oil extracted from organically grown coconuts as a carrier.
With 52 five-star reviews, our CBDA + CBGA Tincture is worth considering if you're looking for these rare hemp cannabinoids.
"I've used CBD products for years and this is an excellent tincture. It's a great product at a reasonable price. Shipping was fast on both of the purchases I've made. I had several questions and the response I received from customer service was prompt, friendly, and helpful. Great people and company!" - Teri, Minnesota
"LOVE this product. Put a dropper in my espresso every morning and it gives me just the best start to my day." - Christopher R., Texas
About Hometown Hero
Founded and based in Austin, Texas, we're a canna-business that supports U.S. veterans through donations made with every purchase. On our website, you can find comprehensive third-party lab results for each one of our products. Plus, we have an in-house customer support team to answer any questions about our products.
Until next time, happy exploring, and mind your mind!
FDA Disclaimer: The statements made regarding these products have not been evaluated by the Food and Drug Administration. The efficacy of these products has not been confirmed by FDA-approved research. These products are not intended to diagnose, treat, cure, or prevent any disease. All information presented here is not meant as a substitute for or alternative to information from health care practitioners. Please consult your healthcare professional about potential interactions or other possible complications before using any product. The Federal Food, Drug, and Cosmetic Act requires this notice.
